HISTIOCITOSIS DE CELULAS NO LANGERHANS PDF

Langerhans Cell Histiocytosis, Hashimoto-Pritzker Type Langerhans Cell Histiocytosis of lung Langerhans Cell Histiocytosis, disseminated clinical Langerhans Cell Histiocytosis, unifocal clinical The disease spectrum results from clonal accumulation and proliferation of cells resembling the epidermal dendritic cells called Langerhans cells , sometimes called dendritic cell histiocytosis. These cells in combination with lymphocytes , eosinophils , and normal histiocytes form typical LCH lesions that can be found in almost any organ. LCH is clinically divided into three groups: unifocal, multifocal unisystem, and multifocal multisystem. It typically has no extraskeletal involvement, but rarely a lesion can be found in the skin, lungs, or stomach.

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Ampliar Figura 1. El permiso para reutilizar la figura se debe solicitar directamente a la Dra. En la actualidad, la HCL se considera una neoplasia mieloide.

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Histiocitosis de células de Langerhans

Este caso ejemplifica la necesidad tanto de pediatras como odontopediatras de estar conscientes que HCL puede simular lesiones periodontales. O tecido facial adjacente encontrava-se intacto e sem sintomatologia. LCH may appear as a single osteolytic lesion or can affect many body systems. This case report involves a 3-year-old boy referred to the pediatric dentistry residency clinic at the University of Puerto Rico to evaluate possible periodontal disease on primary second lower molars. Examination revealed bilateral extra-oral swelling on the left and right side of the face obliterating the mandibular angles. The overlying skin was intact and symptomless. An intraoral examination showed localized swelling of the overlying mucosa from the lower primary right and left molars with some degree of mobility on both the right and left second primary molars.

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Histiocitosis

TABLA 1. These entities make up a heterogeneous group, and are mainly classified as Langerhans cell histiocytoses and non-Langerhans cell histiocytoses. Langerhans cell histiocytoses have as a common characteristic the proliferation of dendritic antigen-presenting cells with phenotypical and ultrastructural characteristics of Langerhans cells. Infiltration may be limited to one organ, or may be disseminated. The prognosis and the treatment especially depend on the age of the patient and the number and dysfunction of the organs involved.

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Histiocitosis de células de Langerhans

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Langerhans cell histiocytosis

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